However, the findings of Takano et al.’s study [18] do not support the above view, they believe that the prognosis of patients with CCNE1 positive expression of gastric cancer was better than that of negative expression and it was speculated that this may be related to the inactivation of CCNE1 (CyclinE)/CDK2 complexes. The gene discussed is CCNE1; the disease is gastric cancer.