Furthermore, we focused on the nine LncRNAs (LINC01088, AK03516, AC003104.1, LINC00261, RP11–17803.2, SMDA5-AS1, TPTEP1, IDH1-AS1 and LINC00341), which were most highly upregulated in HCC cells after 6 or 12 h cisplatinum treatment. The gene discussed is SYNE3; the disease is hepatocellular carcinoma.