Among the four different breast tumor types, CYP epoxygenase products, EETs, were elevated the most in TNBC while several lipoxygenase-derived AA metabolites including lipoxins (LXs), leukotrienes (LTs), 5-HETE and 15-HETE were significantly elevated in ER+/PR+/HER2- or TPBC tumor tissues. The gene discussed is ESR1; the disease is breast neoplasm.