Furthermore, the miR-132-3p, miR-212-3p, and miR-361-5p binding sites in the CD80 gene have been involved in the development and progression of gastric cancer [22] whereas miR-424(322) affects the immune regulation and drug resistance of ovarian cancer by targeting CD80 and CD274 (PD-L1) [43]. The gene discussed is CD274; the disease is ovarian cancer.