FOXM1 and hepatocellular carcinoma: We analyzed cell proliferation rate with the EdU assay and found that it was increased in FOXM1 + sh-Control relative to Empty vector + sh-Control HepG2 cells, but this was abrogated by KIF4A knockdown (FOXM1 + sh-KIF4A) (Fig. 5c), suggesting that FOXM1 promotes HCC cell proliferation via KIF4A.