ACTA1 and neoplasm: Consistent with the idea of the role of MSC and αSMA+ myofibroblasts in tumour progression, tail vein injection of bone marrow-derived MSCs in mice with partial pancreatectomy resulted in recruitment of these cells to the pancreas and their differentiation into PSCs (cells expressing αSMA with similar features of myofibroblast cells), pancreatic ductal epithelial cells, and vascular endothelial cells strongly contributing to the regeneration of the pancreas [18].