CD14 and asthma: CD14+CD16+ (also referred to as CD14++CD16+ ) intermediate monocytes, which expressed high levels of miRNA-124 and exhibited other properties of M2-like cells (M2 surface markers such as CD163, CX3CR1, IL-4R, TGF-β1, and IL-10) [47] have been reported to be increased in patients with severe asthma compared to mild/moderate asthmatics [80].