IGFBP3 and vitamin D deficiency: Leveraging a randomized controlled trial of vitamin D supplementation in pregnancy, the objective of this study was to determine the effect of prenatal vitamin D supplementation on the concentrations of IGF axis proteins (IGF-I, IGF-II, IGFBP-1, IGFBP-3 and the IGF-I/IGFBP-3 molar ratio) at birth in neonates in Bangladesh, where there is a high prevalence of vitamin D deficiency and FGR (2).