Sattar et al [26], in The Elderly at Risk Study, found that elevations in IL-6 levels were significantly more associated with fatal myocardial infarction or stroke death (hazard ratio 1.75 for 1 log unit increase in IL-6) than with risk of nonfatal cardiovascular death (hazard ratio 1.17), even after adjustments; similar trends were found for CRP. This evidence concerns the gene CRP and myocardial infarction.