This study highlighted the genetic heterogeneity across histological subtypes of lung cancer and reported novel loci for lung cancer at 1p31.1 (rs71658797, FUBP1), 6q27 (rs6920364, RNASET2), 8p21.1 (rs11780471, CHRNA2), and 15q21.1 (rs66759488, SEMA6D). The gene discussed is RNASET2; the disease is lung carcinoma.