After intravenous injection, this viral drug carrying a motif derived from von Willebrand coagulation factor (vWF) on its surface selectively binds receptors and collagenous proteins exposed heavily in tumor microenvironment in order to fuse, enter, uncoat, and insert its genetic material randomly in the chromosomes of the actively dividing tumor cells only (184). This evidence concerns the gene VWF and neoplasm.