CXCL10 and viral infectious disease: CXCL10 expression is induced by type I interferons to recruit T lymphocytes into the CNS to protect against neurotropic viral infections (Liuet al., 2000) and it and its receptor, CXCR3, are necessary for induction of experimental cerebral malaria (ECM); probably due to the critical role CXCL10 plays in T cell-endothelial cell adhesion, and injury of the brain endothelium (Sorensenet al., 2018).