WWTR1 and neoplasm: Owing to low tumor cellularity and the absence of EHE cell lines, the specific genes disrupted via the translocation remained unknown until 2011, when Tanaset al. employed RNA sequencing to identify a fusion between the promotor region of WW domain-containing transcription regulator 1 (WWTR1) on 3q25 and the carboxyl terminus of calmodulin-binding transcription activator 1 (CAMTA1) on 1p3639.