MAPT and frontotemporal dementia: Moreover, we and others have shown that altered sociability is a feature of different animal models of FTD, including those based on manipulations of TDP-43, tau, fused in sarcoma (FUS), progranulin, and CHMP2B (Ghoshal et al., 2012; Filiano et al., 2013; Alfieri et al., 2014, 2016; Koss et al., 2016; Vernay et al., 2016; Shiihashi et al., 2017).