To determine whether the levels of α-dicarbonyls and AGEs are increased in the lesions of MS patients compared to white matter of NDCs, post-mortem lesions of 15 MS patients and 10 white matter samples of NDCs were obtained (Table 1) and levels of MGO, GO and free and protein-bound CML, CEL, and MG-H1 were measured. The gene discussed is CEL; the disease is myeloid sarcoma.