Another study demonstrated the ability of tocopherols to reduce systemic oxidative stress, but not inflammatory markers such as hs-CRP, IL-6, TNF-α, or MCP-1 in patients with T2DM after a daily intake of 500 mg/day of α-tocopherol or mixed tocopherols rich in γ-tocopherol for 6 weeks (75). Here, TNF is linked to type 2 diabetes mellitus.