In addition, in all pSS patients, we found that there were 10 (66.67%) clinic indexes in high IgG levels, 14 (93.33%) with focus score ≥ 1, 12 (80%) in anti-SSA positivity, 12 (80%) in anti-SSB positivity and 15 (100%) in ANA positivity (Table 1). The gene discussed is SSB; the disease is peeling skin syndrome.