Ten of our sex impacted disease genes (CYBRD1, DIRAS2, FAM107B, FOS, GMPR, HVCN1, ITIH5, MAPK, RNF135, SLC40A1) did not overlap with their findings, and these genes have been previously associated with oxidative stress, cell signaling and transport, apoptosis and AD. This evidence concerns the gene CYBRD1 and Alzheimer disease.