The administration of Rd after stroke inhibited ischemia-induced microglial activation, decreased the expression levels of various proinflammatory cytokines, and suppressed nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha (IκBα) phosphorylation and NF-κB nuclear translocation (Zhang et al., 2016). This evidence concerns the gene NFKBIA and stroke disorder.