Consistent with the gene expression pattern in OC cells, the levels of total β-catenin, phosphorylated β-catenin (Ser33/37/Thr41), cyclin D1, p53, PUMA, E-cadherin, and N-cadherin were also regulated in miR-340-overexpressing tumor samples from nude mice as shown by immunoblot analysis (Fig. 8a). This evidence concerns the gene CDH2 and neoplasm.