LMP induction in glioblastoma treatment has not been widely studied, but several studies have recently characterized the mechanism of action of some novel chemotherapeutics and shown that lysosomal dysfunction is a major contributor in drug‐mediated cancer cell death (Gonzalez et al, 2012; Gutierrez et al, 2016; Jiang et al, 2016). The gene discussed is PDLIM7; the disease is glioblastoma.