LAMP1 and psoriasis: In general, the data clearly demonstrate that there was an increase in the quantity of lysosomes (LAMP1) with a reduction in the total amount of acidic vesicular structures (LysoTracker Red), while maintaining the membrane integrity of these structures (AO), in the keratinocytes of HaCaT with “psoriasis-like” inflammation as compared with the non-activated keratinocytes with a differentiated phenotype (2 mM Ca2+).