Regarding BRCA1 and BRCA2, both of these genes showed similar strong positive correlations with UBE2C in different cancers (Table 2 and Table S1 file), but a negative correlation was observed for BRCA1 in THCA and for BRCA2 in TGCT (Table 2 and Supplementary Data Table S1). The gene discussed is BRCA1; the disease is cancer.