In relation to the expression correlation between UBE2C and tumor suppresser genes including BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), BRCA1, BRCA2 DNA repair associated (BRCA2), checkpoint kinase 2 (CHK2), ATM serine/threonine kinase (ATM), ATR, tumor protein p53 (TP53), CYLD, and TSPYL2, the positive correlation between BUB1B and UBE2C was seen in 26 cancers, but not in TGCT cancer (Table 2 and Supplementary Data Table S1). The gene discussed is CYLD; the disease is cancer.