BRCA2 and breast cancer: In the majority of cases, however, the clinical phenotype ofPALB2-BC resembles that of BRCA2-BC, since both are predominantly ER- andPR-positive (Bane et al.,2007; Tischkowitz etal., 2007; Teoet al., 2013; Antoniou et al., 2014; Cybulski et al., 2015; Nguyen-Dumont et al.,2015).