BRCA1 and neoplasm: Interestingly, BRCA1, BRCA2 andPALB2 heterozygous mice could not be distinguished from wild-type animals,corroborating the classic recessive model for tumor suppression, at least in animalmodels (Gowen et al., 1996;Sharan et al., 1997;Rantakari et al.,2010).