For example, miR‐1247 could aggravate acute pneumonia through activating JNK and NF‐κB pathways, and CRNDE can upregulate FOXM1 that further activates NF‐κB and JAK/STAT pathways in LPS‐injured WI‐38 cells.35, 45 Because of the key function of JAK/STAT and NF‐κB in pneumonia, our data prove that XIST knockdown contributes to inhibition of JAK/STAT and NF‐kB pathways through sponging miR‐370‐3p during pneumonia progression. The gene discussed is MAPK8; the disease is pneumonia.