Although etiology of MS still remains unknown, it is considered an immune‐mediated disease in which myelin‐reactive CD4+ T lymphocytes trigger a complex immune response that leads to inflammation, myelin destruction, and axonal loss.17, 18, 19 The main players initiating the autoimmune attack are autoreactive CD4+ Th1 and Th17 cells, which produce pro‐inflammatory cytokines, such as IFN‐γ and IL‐17, respectively. This evidence concerns the gene IFNG and myeloid sarcoma.