STAT3 has been reported to be intimately associated with β‐Catenin‐mediated EMT potential and CSC activity in various malignancies.41, 42 These results raised our interest concerning whether the miR‐125b‐5p/STAT3 axis produced the EMT and CSC inhibition through β‐Catenin in hepatoma cells. The gene discussed is STAT3; the disease is hepatocellular carcinoma.