To verify that the tumor suppressive roles of miR‐125b‐5p in liver cancer were achieved via inhibiting STAT3, we introduced a STAT3 eukaryotic expression plasmid into HCCLM3 and HUH7 cells to induce WT‐STAT3‐3′UTR independent ectopic STAT3 expression. The gene discussed is STAT3; the disease is liver cancer.