We have shown before, that within cells of the most frequent nonmelanoma skin cancer basal cell carcinoma, and other adnexal benign or malignant proliferations such as sebaceous adenoma or carcinoma and eccrine sweat gland tumours such as sebaceous carcinomas and porocarcinomas, stem cell markers such as Lrig1-, Lgr5-, Sox9 are preserved. This evidence concerns the gene LRIG1 and eccrine porocarcinoma.