MMP15 and neoplasm: For example, Zhang et al. [26] showed that PICART1 functioned as a tumor suppressor that suppressed cell proliferation and invasion partly through regulating AKT signaling pathway.Liu et al. reported that LncRNA MAFG-AS1 could promote NSCLC cells growth and metastasis through acting as an miR-339 sponge to regulate MMP15 [27].