Both campaigns provided robust mouse data consistent with human genetic disorders involving mutations of ALPK3, ANGPT4, DAGLA, DUOXA2, LRRK1 and SLC24A5. Lrrk1 mice have the highest body volumetric BMD and BMD values in the Lexicon and IMPC screens, respectively (Fig. S1). This evidence concerns the gene LRRK1 and hereditary disease.