Punctate Gallyas-Braak silver staining positive structures indicative of axonal tau aggregates accumulated in the alveus and the dorsal fornix close to the injection site in two AD CSF inoculated mice, reminiscent of a similar pathology induced in the fornix of P301S tau mice seeded with P301S tau mouse donor brain extracts [1]. The gene discussed is MAPT; the disease is Alzheimer disease.