A recent study [75], using colorectal adenocarcinoma NCI-H716 cells as an in vitro model of gastrointestinal cells, showed that isoquercitrin (5) is a promising compound to treat type 2 diabetes since it was identified as a DPP-IV inhibitor, with an IC50 of 96.8 μM. This evidence concerns the gene DPP4 and type 2 diabetes mellitus.