TNF and Arthritis: The aims of our study were (i) the longitudinal characterization of pattern and intensity of joint inflammation in a TNF‐driven erosive mouse model of arthritis; (ii) to differentiate joint inflammation in vivo and bone remodeling processes in vivo from bone damage; and (iii) to evaluate the reversibility of these events in individual animals during therapeutic intervention, such as anti‐TNF antibody (anti‐TNF), using [18F]FDG PET, [18F]fluoride PET, and CT.