Previous work using a mouse infection model suggested that LPCs may aid recovery from acute infection.[20, 21] Injection of LPC before experimental Acinetobacter baumannii peritoneal sepsis or pneumonia did reduce lethality and bacterial burdens.[20, 21] Other possible explanations for low LPC concentrations in acute CAP include increased activity of the LPC-degrading enzyme autotaxin. Here, ENPP2 is linked to infection.