In this study, we developed lines containing two blast resistance genes Y58S (Pi37/Pid3), GZ63S (Pi5/Pi54), GZ63S (Pi54/Pid3) and C815S (Pigm/Pid37) that were highly resistant to leaf and neck blast under natural infection conditions, and the phenotypes showed that the effect on neck blast was better than on leaf blast in the Y58S, GZ63S and C815S backgrounds. The gene discussed is SERPINB5; the disease is infection.