PTX3 significantly correlated with the histological stage of liver fibrosis (rho = 0.64, P < 0.001), and the levels of PTX3 were significantly higher in patients with significant fibrosis (F≥2) compared to F0-F1 (P < 0.001) (Figure 1(b)). The gene discussed is PTX3; the disease is Hepatic fibrosis.