RUNX1 and breast cancer: A gene signature including the top 10 genes (see Supplementary Methods for gene names in the signature) induced by CBFB and RUNX1 significantly predicted the Disease-Free Survival Probability of breast cancer patients from TCGA (The Cancer Genome Altas)24 and the Disease Specific Survival of breast cancer patients from METABRIC25 (Fig. 7b and Supplementary Fig. 8a).