While earlier SELEX experiments identified the binding aptamer sequence (G/A)UnAGU (n = 1 − 3)51, iCLIP experiments with Msi1 in human glioblastoma cells confirmed the preferential binding of Msi1 to single-stranded (stem-loop) UAG sequences in 3′UTRs, but not in coding regions57. This evidence concerns the gene MSI1 and glioblastoma.