Immunohistochemistry revealed that there were similar numbers of CD45+ leukocytes, neutrophils (MPO+), T cells (CD3+), astrocytes (GFAP+) (Supplementary Fig. S2) and microglia-macrophages (Fig. 6A) in the ischemic hemisphere of WT compared with IL-37tg mice after stroke. Here, MPO is linked to stroke disorder.