Similarly, the expression of il-1β, a key regulator of inflammation, increased only slightly during first three days with a maximum 1.5-fold increase at 2 dpi and a subsequent decrease below the expression level observed in control fish, likely indicating inhibition, from 7 dpi onward and for the remainder of the experimental infection (lower expression over time when compared to initial dpi, LM: F(11,44) = 9.1, P < 0.001 to 0.014). The gene discussed is IL1B; the disease is infection.