To further explore the relevance of the capacity of HNF4α to recruit the DNA damage response protein partners in colorectal cancer, HCT116 cells that are devoid of the HNF4α expression [11,33] were used to stably express the P2-BirA recombinant protein and to perform a BioID analysis similarly to what was done in the HEK293T cells. This evidence concerns the gene HNF4A and colorectal cancer.