According to previous reports of comorbidities associated with 21‐OHD, only two females were reported with Turner's syndrome (Larizza et al., 1994; Montemayor‐Jauregui, Ulloa‐Gregori, & Flores‐Briseno, 1985) and ornithine transcarbamylase (OTC) deficiency (Kim et al., 2013). This evidence concerns the gene OTC and hyperinsulinemic hypoglycemia, familial, 4.