Cystic growth is driven by a combination of abnormal proliferation of cyst lining cells and transepithelial fluid secretion into cyst lumen, a process driven by intracellular 3', 5'- cyclic adenosine monophosphate (cAMP) via apical cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel [6–11]. The gene discussed is CFTR; the disease is cyst.