We performed ChIPseq using HCT116 colon carcinoma cells, identifying ~850 putative target genes associated with metabolism (e.g., Prdx5, Mdh1, Ahcy), transcription (Taf12, Tet2, histones), malignancy (Met, Blcap, Rras, Jag1, Gsk3a) and mitotic stability (Zbtb4). Here, AHCY is linked to colon carcinoma.