EGFR and neoplasm: EGCG inhibited the binding of EGF and EGFR in the esophageal cancer cell, KYSE150, which changed the membrane dimerization and activation of the EGFR tissue [99], inhibited the activation of RTKs related to other membranes, blocked the metabolic pathway to induce cell growth cycle arrest, and ultimately, blocked tumor angiogenesis and metastasis.