EGCG inhibited the binding of EGF and EGFR in the esophageal cancer cell, KYSE150, which changed the membrane dimerization and activation of the EGFR tissue [99], inhibited the activation of RTKs related to other membranes, blocked the metabolic pathway to induce cell growth cycle arrest, and ultimately, blocked tumor angiogenesis and metastasis. Here, EGFR is linked to esophageal cancer.