GFAP and hydrops fetalis: Genetic ablation of αE-catenin in murine epidermis (using K14-Cre mice) or more specifically in the HF bulge (using GFAP-Cre mice) led to a hyperproliferative phenotype that was caused by increased nuclear abundance of YAP in the basal and suprabasal epidermal cell layers [99,101,121].