Compared with the survival group, a greater proportion of the death group was HER2 positive (p = 0.040), ER positive (p < 0.001), PR positive (p = 0.001), with tumor size ≥ 2.0 cm (p < 0.001), lymph node positive (p < 0.001), LVI positive (p < 0.001), with dermal invasion (p = 0.009), with perineural invasion (p < 0.001), with total mastectomy (p < 0.001), without chemotherapy treatment (p = 0.004), and without hormone therapy (p < 0.001). The gene discussed is ESR1; the disease is neoplasm.