EGFR and non-small cell lung carcinoma: Additionally, the frequency of classical types of EGFR mutations (Del 19, L858R) appear to be lower than in NSCLC (~7.5% of EGFR mutated each), favoring rare mutation types, including Exon 18 (G719D/S, G696R, S695N/D, N700D, I715F, L688F, P694L), Exon 19 (K757N, A755V, V742I, E736K, N756Y, E749K, P753L, A755T), Exon 20 (T790M, H773R, S768R/N, R776H/C, G796D, D807N, R803W/Q, Y813C, G810S, A763T, G779D, Q791R, C781Y, N771S) and Exon 21 (L858V, G874R, K867E) (11).