Their coexpression was detected in normal gastric mucosa, hyperplastic polyp, intestinal metaplasia, gastric intraepithelial neoplasia, and adenocarcinoma, showing highly elevated expression from benign proliferative lesions to malignant lesions, suggesting that SOX9 could change CEACAM1 expression patterns, which might promote the tumor progression [99]. The gene discussed is SOX9; the disease is neoplasm.