However, upon pathogen infection or treatment with exogenous SA, a change in the cellular redox system occurs, that has been associated with the SA-triggered suppression of JA responses (Holuigue et al., 2016), which induces NPR1-complex dissociation to monomers, by the reduction of disulfide links (Figure 1B) (Tada et al., 2008). The gene discussed is NPR1; the disease is infection.